(E)-2-[4-(Piperidin-1-yl)benzylidene]-2,3-dihydro-1H-inden-1-one
نویسندگان
چکیده
In the title compound, C(21)H(21)NO, the indene ring system is essentially planar with a maximum deviation of 0.066 (1) Å and makes dihedral angles of 7.93 (6) and 2.43 (6)°, respectively, with the benzene plane and the mean plane of the piperidine ring. These latter two planes make a dihedral angle of 7.61 (7)°. In the crystal, mol-ecules are linked by C-H⋯O inter-actions, forming infinite chains along the b axis.
منابع مشابه
Molecular structure studies of (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol
The single enantiomer (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol (2), has recently been synthesized and isolated from its corresponding diastereoisomer (1). The molecular and crystal structures of this novel compound have been fully analyzed. The relative and absolute configurations have been determined by using a combination of analytical tools including X-ray crystallography...
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Antagonists of the vanilloid receptor TRPV1 (transient receptor potential vanilloid type 1) have been reported to produce antihyperalgesic effects in animal models of pain. These antagonists, however, also caused concomitant hyperthermia in rodents, dogs, monkeys, and humans. Antagonist-induced hyperthermia was not observed in TRPV1 knockout mice, suggesting that the hyperthermic effect is excl...
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In the title mol-ecule, C(17)H(11)F(3)O, the indan ring system and the trifluoro-methyl-substituted benzene ring are approximately individually planar and form a dihedral angle of 1.81 (5)° with each other. In the crystal, mol-ecules are linked by pairs of weak bifurcated (C-H)(2)⋯O hydrogen bonds to form centrosymmetric dimers, generating R(2) (1)(6) and R(2) (2)(10) ring motifs. These dimers ...
متن کاملFor the use of Registered Medical Practitioner or a Hospital or a Laboratory only
OD-PEP (a Fixed dose combination of Pantoprazole and Domperidone) contains Pantoprazole which is chemically sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2pyridinyl)methyl]sulfinyl]-1H-benzimidazole sesquihydrate and Domperidone which is chemically 5-chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]-piperidin-4 -yl]1,3-dihydro-2H-benzimidazol-2-one. OD-PEP capsule is Transparent/Tr...
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In the title compound, C(17)H(12)O(3), each of the five-membered rings in the inden-1-one and 1,3-benzodioxole residues is almost planar (r.m.s. deviations = 0.041 and 0.033 Å, respectively). A small twist about the single bond linking the two residues is evident [the C-C-C-C torsion angle = 8.7 (4)°]. Supra-molecular zigzag layers propagating in the ac plane are formed in the crystal via C-H⋯O...
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